What medication class is often used to treat PTSD?

Prepare for the Rosh Psychiatry Board Exam with detailed flashcards and multiple choice questions complete with explanations. Enhance your readiness to excel!

Selective Serotonin Reuptake Inhibitors (SSRIs) are frequently prescribed as a first-line treatment for Post-Traumatic Stress Disorder (PTSD). This class of medications works by increasing the levels of serotonin in the brain, which can help improve mood and reduce anxiety, symptoms commonly associated with PTSD. Evidence from clinical studies supports the efficacy of SSRIs in alleviating both re-experiencing symptoms (such as flashbacks and intrusive thoughts) and avoidance behaviors, making them a central component in the management of this disorder.

SSRIs are preferred due to their favorable side effect profile and the lower potential for misuse, particularly in comparison to other classes of medications. This means that they can be used safely in a broader range of patients, including those with comorbid conditions. Furthermore, the therapeutic effects can take several weeks to become fully evident, which requires careful monitoring and support during the initial stages of treatment.

In contrast, other classes mentioned may not have the same level of supporting evidence or therapeutic benefit in treating PTSD. Tricyclic antidepressants can be effective but are often associated with more side effects, which can limit their use. Benzodiazepines might provide short-term relief for anxiety but are not recommended for long-term treatment of

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