What is a common first-line treatment option for bipolar disorder during a manic episode?

Mood stabilizers, particularly lithium, are commonly recognized as first-line treatment options for managing manic episodes in individuals with bipolar disorder. The mechanism of action of lithium helps to stabilize mood by reducing the intensity of mood swings, and it has demonstrated efficacy in both the acute treatment of mania and the long-term management of the disorder.

During a manic episode, the goal is to achieve rapid stabilization of mood and minimize risks such as impulsive behavior, aggression, or psychosis, which may accompany manic states. Lithium's ability to effectively reduce manic symptoms makes it a preferred choice in this acute setting.

Other treatments may be considered, but they serve different roles or are not as effective in acute manic episodes. Antidepressants can sometimes exacerbate mania and are generally avoided unless used alongside mood stabilizers. While antipsychotics can also help manage symptoms during manic episodes, they are often used in conjunction with mood stabilizers rather than as singular first-line treatment. Psychotherapy alone is not effective in the acute setting for managing mania and is typically reserved for maintenance therapy or after stabilization of mood has been achieved.